Denosumab Therapy for Giant Cell Tumor of Bone Pulmonary Metastasis
نویسندگان
چکیده
منابع مشابه
Denosumab Therapy for Giant Cell Tumor of Bone Pulmonary Metastasis
CASE A 68-year-old female was diagnosed with giant cell tumor of bone (GCTB) metastatic to her lungs. The patient was treated with IV denosumab for the course of 4.5 years for these metastases. The metastatic tumor burden decreased significantly after only 3 months of therapy. The size of the metastases has been stable for over 4 years. CONCLUSION Denosumab therapy has promise in the treatmen...
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Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. Its histogenesis remains unclear. It is characterized by a proliferation of mononuclear stromal ...
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STUDY DESIGN A case report. OBJECTIVE To report a case of the lumbar giant cell tumor (GCT) utilizing a new clinical treatment modality (denosumab therapy), which showed a massive tumor reduction combined with the L4 spondylectomy. SUMMARY OF BACKGROUND DATA There are some controversies about spinal GCT treatments. Denosumab has provided good clinical results in terms of tumor shrinkage, an...
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Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthesis of the knee joint. We have treated her with denosumab, which is a receptor activator of nuclea...
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ژورنال
عنوان ژورنال: Case Reports in Orthopedics
سال: 2017
ISSN: 2090-6749,2090-6757
DOI: 10.1155/2017/2302597